Process understanding, in real time.
Near-Infrared Process Analytical Technology, integrated directly with your blending systems — turning quality control into proactive process assurance.
From reactive testing to proactive assurance
With agitated blending, the agitator mounted along the axis of rotation keeps the powder mass in continuous motion, ensuring the agitator stays fully submerged for consistent, high-energy mixing. This enables faster, more even dispersion without particle damage — reducing blending time and eliminating multi-stage processing. In applications such as pigment dispersion, Agiblend achieves uniform results with ease and repeatability.
Without PAT
End-point testing
Thief sampling disrupts containment
Issues detected only after the batch
Failures mean reprocessing or scrap
Lab queues delay release
With NiR PAT
Continuous in-line monitoring
No physical sampling — containment intact
Deviations caught and corrected live
Endpoint determined by data, not the clock
Real-Time Release Testing enabled
Why NiR PAT
Real-time process understanding
Continuous insight into what's happening inside your process — not just at the endpoint.
Early detection & intervention
Identify deviations live — correct course before batches fall out of specification.
Fewer non-conforming batches
Catch potential issues early — adjust or recover before they cost the batch.
No physical sampling
No thief sampling — containment, operator safety and product integrity maintained.
Supports quality by design
Embeds quality into the process for built-in consistency, predictability and regulatory confidence.
Enables real-time release
Validated PAT systems provide assurance for RTRT — shorter turnaround, full compliance.
How Terriva integrates NiR PAT
Our blending systems are engineered with PAT compatibility built in. NiR sensors mount directly to MultiBlend and Agiblend systems — monitoring blend uniformity and moisture in real time, without interrupting the process.
Seamless integration
MultiBlend and Agiblend systems are engineered for direct NiR mounting — measuring through the vessel without process disruption.
Enhanced process understanding
Continuous feedback on powder homogeneity, particle behaviour and endpoint determination — used to optimise cycle times and strengthen process validation.
21 CFR Part 11-ready data
Data captured under 21 CFR Part 11-ready electronic records, supporting full audit trail and validated e-signatures.
Regulatory context
PAT is recognised by the FDA and EMA as a framework for building quality into pharmaceutical manufacturing. Validated PAT enables Real-Time Release Testing — releasing product based on in-process data rather than end-product testing — substantially reducing release time without compromising compliance.
Works with
NiR PAT integration is supported on MultiBlend and Agiblend systems, paired with Terriva’s 21 CFR Part 11-ready control software.
Next steps
Want to integrate NiR PAT into your blending operation?
Our application engineers will assess your formulation, recommend sensor configuration and walk through validation, integration and release-testing implications.
